Publications
Fitz, N. F., J. Wang, M. I. Kamboh, R. Koldamova and I. Lefterov (2021). "Small nucleolar RNAs in plasma extracellular vesicles and their discriminatory power as diagnostic biomarkers of Alzheimer's disease." Neurobiology of Disease 159: 105481.
Fitz, N. F., K. N. Nam, C. M. Wolfe, F. Letronne, B. E. Playso, B. E. Iordanova, T. D. Y. Kozai, R. J. Biedrzycki, V. E. Kagan, Y. Y. Tyurina, X. Han, I. Lefterov and R. Koldamova (2021). "Phospholipids of APOE lipoproteins activate microglia in an isoform-specific manner in preclinical models of Alzheimer’s disease." Nature Communications 12(1): 3416.
Fitz, N. F., C. M. Wolfe, B. E. Playso, R. J. Biedrzycki, Y. Lu, K. N. Nam, I. Lefterov and R. Koldamova (2020). "Trem2 deficiency differentially affects phenotype and transcriptome of human APOE3 and APOE4 mice." Mol Neurodegener 15(1): 41.
Fitz, N. F., K. N. Nam, R. Koldamova and I. Lefterov (2019). "Therapeutic targeting of nuclear receptors, liver X and retinoid X receptors, for Alzheimer's disease." Br J Pharmacol 176(18): 3599-3610.
Lefterov, I., C. M. Wolfe, N. F. Fitz, K. N. Nam, F. Letronne, R. J. Biedrzycki, J. Kofler, X. Han, J. Wang, J. Schug and R. Koldamova (2019). "APOE2 orchestrated differences in transcriptomic and lipidomic profiles of postmortem AD brain." Alzheimers Res Ther 11(1): 113.
Castranio, E. L., C. M. Wolfe, K. N. Nam, F. Letronne, N. F. Fitz, I. Lefterov and R. Koldamova (2018). "ABCA1 haplodeficiency affects the brain transcriptome following traumatic brain injury in mice expressing human APOE isoforms." Acta Neuropathologica Communications 6(1).
Nam, K. N., C. M. Wolfe, N. F. Fitz, F. Letronne, E. L. Castranio, A. Mounier, J. Schug, I. Lefterov and R. Koldamova (2018). "Integrated approach reveals diet, APOE genotype and sex affect immune response in APP mice." Biochim Biophys Acta Mol Basis Dis 1864(1): 152-161.
Wolfe, C., N. Fitz, K. Nam, I. Lefterov and R. Koldamova (2018). "The Role of APOE and TREM2 in Alzheimer′s Disease—Current Understanding and Perspectives." International Journal of Molecular Sciences 20(1): 81.
Nam, K. N., A. Mounier, C. M. Wolfe, N. F. Fitz, A. Y. Carter, E. L. Castranio, H. I. Kamboh, V. L. Reeves, J. Wang, X. Han, J. Schug, I. Lefterov and R. Koldamova (2017). "Effect of high fat diet on phenotype, brain transcriptome and lipidome in Alzheimer's model mice." Sci Rep 7(1): 4307.