University of Pittsburgh

The Koldamova/ Lefterov Lab

 

 

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Pending Publications

Publications

  • Carter, A. Y., F. Letronne, N. F. Fitz, A. Mounier, C. M. Wolfe, K. N. Nam, V. L. Reeves, H. Kamboh, I. Lefterov and R. Koldamova
    Liver X receptor agonist treatment significantly affects phenotype and transcriptome of APOE3 and APOE4 Abca1 haplo-deficient mice. .
    PLoS One 2017; 12(2): e0172161
    PMID:28241068
  • Castranio, E. L., A. Mounier, C. M. Wolfe, K. N. Nam, N. F. Fitz, F. Letronne, J. Schug, R. Koldamova and I. Lefterov
    Gene co-expression networks identify Trem2 and Tyrobp as major hubs in human APOE expressing mice following traumatic brain injury. .
    Neurobiol Dis 2017; 105: 1-14.
    PMID:28502803
  • Cronican, A. A., N. F. Fitz, A. Carter, M. Saleem, S. Shiva, A. Barchowsky, R. Koldamova, J. Schug and I. Lefterov.
    ABCA1 Deficiency Affects Basal Cognitive Deficits and Dendritic Density in Mice. .
    J Alzheimers Dis. 2017
    PMID:23405071
  • Fitz, N. F., A. Y. Carter, V. Tapias, E. L. Castranio, R. Kodali, I. Lefterov and R. Koldamova.
    Genome-wide alteration of histone H3K9 acetylation pattern in mouse offspring prenatally exposed to arsenic. .
    PLoS One 2013; 8(2): e53478.
    PMID:28106559
  • Fitz, N. F., E. L. Castranio, A. Y. Carter, R. Kodali, I. Lefterov and R. Koldamova.
    Improvement of memory deficits and amyloid-beta clearance in aged APP23 mice treated with a combination of anti-amyloid-beta antibody and LXR agonist. .
    J Alzheimers Dis 2014; 41(2): 535-549.
    PMID:24643138
  • Fitz, N. F., A. A. Cronican, I. Lefterov and R. Koldamova.
    Comment on "ApoE-directed therapeutics rapidly clear beta-amyloid and reverse deficits in AD mouse models. .
    JScience 2013; 340(6135): 924-c.
    PMC:PMC4086452
  • Fitz, N. F., A. A. Cronican, M. Saleem, A. H. Fauq, R. Chapman, I. Lefterov and R. Koldamova.
    Abca1 deficiency affects Alzheimer's disease-like phenotype in human ApoE4 but not in ApoE3-targeted replacement mice. .
    J Neurosci 2012; 32(38): 13125-13136.
    PMID:22993429
  • Fitz, N. F., V. Tapias, A. A. Cronican, E. L. Castranio, M. Saleem, A. Y. Carter, M. Lefterova, I. Lefterov and R. Koldamova.
    Opposing effects of Apoe/Apoa1 double deletion on amyloid-beta pathology and cognitive performance in APP mice. .
    Brain 2015; 138(Pt 12): 3699-3715.
    PMID:26510953
  • Koldamova, R., N. F. Fitz and I. Lefterov.
    ATP-binding cassette transporter A1: from metabolism to neurodegeneration. .
    Neurobiol Dis 2014; 72 Pt A: 13-21.
    PMID:24844148
  • Koldamova, R., J. Schug, M. Lefterova, A. A. Cronican, N. F. Fitz, F. A. Davenport, A. Carter, E. L. Castranio and I. Lefterov.
    Genome-wide approaches reveal EGR1-controlled regulatory networks associated with neurodegeneration. .
    Neurobiol Dis 2014; 63: 107-114.
    PMID:24269917
  • Lefterov, I. and R. Koldamova.
    Metabolic Disorders and Neurodegeneration, introduction to the special issue. .
    Neurobiol Dis 2014; 72 Pt A: 1-2.
    PMID:25301714
  • Lefterov, I., J. Schug, A. Mounier, K. N. Nam, N. F. Fitz and R. Koldamova.
    RNA-sequencing reveals transcriptional up-regulation of Trem2 in response to bexarotene treatment. .
    Neurobiol Dis 2015; 82: 132-140.
    PMID:26071899
  • Mounier, A., D. Georgiev, K. N. Nam, N. F. Fitz, E. Castranio, C. Wolfe, A. A. Cronican, J. Schug, I. Lefterov and R. Koldamova.
    Bexarotene-Activated Retinoid X Receptors Regulate Neuronal Differentiation and Dendritic Complexity. .
    Journal of Neuroscience 2015; 35(34): 11862-11876.
    PMID:26311769
  • Nam, K. N., A. Mounier, N. F. Fitz, C. Wolfe, J. Schug, I. Lefterov and R. Koldamova.
    RXR controlled regulatory networks identified in mouse brain counteract deleterious effects of Abeta oligomers. .
    Sci Rep 2016; 6: 24048
    PMC:PMC4823697
  • Sweet, R. A., M. L. MacDonald, C. M. Kirkwood, Y. Ding, T. Schempf, J. Jones-Laughner, J. Kofler, M. D. Ikonomovic, O. L. Lopez, M. E. Garver, N. F. Fitz, R. Koldamova and N. A. Yates.
    Apolipoprotein E*4 (APOE*4) Genotype Is Associated with Altered Levels of Glutamate Signaling Proteins and Synaptic Coexpression Networks in the Prefrontal Cortex in Mild to Moderate Alzheimer Disease. .
    Mol Cell Proteomics 2016; 15(7): 2252-2262.
    PMID:27103636